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The course, which spans two thirds of a semester, provides students with a research-inspired laboratory experience that introduces standard biochemical techniques in the context of investigating a current and exciting research topic, acquired resistance to the cancer drug Gleevec. Techniques include protein expression, purification, and gel analysis, PCR, site-directed mutagenesis, kinase activity assays, and protein structure viewing.
This class is part of the new laboratory curriculum in the MIT Department of Chemistry. Undergraduate Research-Inspired Experimental Chemistry Alternatives (URIECA) introduces students to cutting edge research topics in a modular format.
AcknowledgmentsDevelopment of this course was funded through an HHMI Professors grant to Professor Catherine L. Drennan.
| Source | MIT 開放式課程 |
| Department | Chemistry |
| Language | English |
| Number of videos | 0 |